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Showing 1 to 12 of 302 entries
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Effect of trenbolone acetate plus estradiol on transcriptional regulation of metabolism pathways in bovine liver.

Hormone molecular biology and clinical investigation

Becker C, Riedmaier I, Reiter M, Tichopad A, Pfaffl MW, Meyer HH.
PMID: 25961197
Horm Mol Biol Clin Investig. 2010 Aug 01;2(2):257-65. doi: 10.1515/HMBCI.2010.029.

BACKGROUND: The use of anabolic steroids is forbidden for food producing animals in the EU. Owing to the advantages of anabolics for production profitability, illegal application is appealing. Anabolics are known to influence gene expression of several tissues. We...

Cancer protection of soy resembles cancer protection during pregnancy.

Hormone molecular biology and clinical investigation

Rohr UD, Gocan AG, Bachg D, Schindler AE.
PMID: 25961211
Horm Mol Biol Clin Investig. 2010 Dec 01;3(2):391-409. doi: 10.1515/HMBCI.2010.063.

It has been established that carrying a pregnancy to full-term at an early age can protect against contracting cancer by up to 50% in later life. The trophoblast theory of cancer states that trophoblast and cancer tissue are very...

Biological responses of progestogen metabolites in normal and cancerous human breast.

Hormone molecular biology and clinical investigation

Pasqualini JR, Chetrite GS.
PMID: 25961215
Horm Mol Biol Clin Investig. 2010 Dec 01;3(3):427-35. doi: 10.1515/HMBCI.2010.066.

At present, more than 200 progestogen molecules are available, but their biological response is a function of various factors: affinity to progesterone or other receptors, their structure, the target tissues considered, biological response, experimental conditions, dose, method of administration...

Androgen modulation of pro-inflammatory and anti-inflammatory cytokines during preadipocyte differentiation.

Hormone molecular biology and clinical investigation

Pierotti S, Lolli F, Lauretta R, Graziadio C, Di Dato C, Sbardella E, Tarsitano MG, Isidori A, Bonifacio V, Lenzi A, Isidori AM.
PMID: 25961224
Horm Mol Biol Clin Investig. 2010 Dec 01;4(1):483-8. doi: 10.1515/HMBCI.2010.059.

BACKGROUND: Macrophages and adipocytes contribute to release of cytokines resulting in the chronic inflammatory profile of the metabolic syndrome. The local increase of proinflammatory cytokines impairs adipogenesis, resulting in formation of dysfunctional adipocytes that are unable to store and...

Intravaginal DHEA, by a strictly local action, exerts beneficial effects on both vaginal atrophy symptoms and sexual dysfunction.

Hormone molecular biology and clinical investigation

Labrie F.
PMID: 25961226
Horm Mol Biol Clin Investig. 2010 Dec 01;4(1):499-507. doi: 10.1515/HMBCI.2010.064.

BACKGROUND: Following complete cessation of estrogen secretion by the ovaries at menopause, all estrogens and practically all androgens are made from dehydroepiandro-sterone (DHEA) of adrenal/ovarian origin. Although being an inactive molecule itself, DHEA is transformed at various levels and...

The relationship between testosterone deficiency and frailty in elderly men.

Hormone molecular biology and clinical investigation

Saad F.
PMID: 25961229
Horm Mol Biol Clin Investig. 2010 Dec 01;4(1):529-38. doi: 10.1515/HMBCI.2010.060.

The vulnerable health status usually preceding the onset of overt disability is often referred to as frailty. A stringent definition is elusive but it can be viewed as a physiological syndrome, characterized by decreased reserve and diminished resistance to...

Hormones and the brain.

Hormone molecular biology and clinical investigation

Garcia-Segura LM, F De Nicola A.
PMID: 25961269
Horm Mol Biol Clin Investig. 2011 Feb 01;7(2):315. doi: 10.1515/HMBCI.2011.124.

No abstract available.

Corticosteroid receptor signalling modes and stress adaptation in the brain.

Hormone molecular biology and clinical investigation

Meijer OC.
PMID: 25961270
Horm Mol Biol Clin Investig. 2011 Feb 01;7(2):317-26. doi: 10.1515/HMBCI.2011.114.

Adrenal glucocorticoid hormones modulate neuronal activity to support an adaptive response to stress. They modulate brain circuitry mediating physiological responses, emotion and cognitive processing. Chronically elevated glucocorticoid exposure is however linked to the development of mental disease. Glucocorticoid effects...

Regulation of the hypothalamic-pituitary-adrenal axis by neuropeptides.

Hormone molecular biology and clinical investigation

Aguilera G.
PMID: 25961271
Horm Mol Biol Clin Investig. 2011 Oct 01;7(2):327-36. doi: 10.1515/HMBCI.2011.123.

The major endocrine response to stress occurs via activation of the hypothalamic-pituitary-adrenal (HPA) axis, leading ultimately to increases in circulating glucocorticoids, which are essential for the metabolic adaptation to stress. The major players in the HPA axis are the...

Leptin and the brain.

Hormone molecular biology and clinical investigation

Chowen JA, Argente J.
PMID: 25961273
Horm Mol Biol Clin Investig. 2011 Oct 01;7(2):351-60. doi: 10.1515/HMBCI.2011.113.

Leptin, which comes from the Greek root leptos meaning thin, has been the focus of intense investigation since its discovery in 1994. This hormone belongs to the cytokine family and is produced by adipocytes and circulates in proportion to...

Sex hormone-binding globulin in congenital adrenal hyperplasia.

Hormone molecular biology and clinical investigation

Zamrazilová L, Dvořáková M, Lisá L, Stárka L, Hampl R.
PMID: 25961974
Horm Mol Biol Clin Investig. 2010 Jan 01;1(2):89-93. doi: 10.1515/HMBCI.2010.008.

BACKGROUND: Sex hormone-binding globulin biosynthesis is influenced by three hormonal systems: gonadal, insular and thyroid. Congenital adrenal hyperplasia is characterized by overproduction of adrenal androgens associated with impaired insulin sensitivity, hyperinsulinemia and often also with hypothyroidism. Only scarce data...

The use of peptide analogs for the treatment of gastrointestinal, pancreatic, liver and urinary bladder cancers.

Hormone molecular biology and clinical investigation

Szepeshazi K, Block NL, Schally AV.
PMID: 25961976
Horm Mol Biol Clin Investig. 2010 Jan 01;1(3):103-10. doi: 10.1515/HMBCI.2010.018.

Peptide hormones can influence the development and growth of many cancers which are not considered classical hormone-dependent tumors. Analogs of somatostatin, bombesin/gastrin-releasing peptide (GRP), luteinizing hormone-releasing hormone (LH-RH) and growth hormone-releasing hormone (GH-RH) can interfere with receptors on tumor...

Showing 1 to 12 of 302 entries